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Botulinum toxin in cancer therapy-current perspectives and limitations
(2021)
Different serotypes of botulinum toxins (BoNTs) act upon different types of SNARE proteins. This property is used in aesthetic medicine to treat certain eye disorders such as crossed eyes (strabismus) and uncontrolled ...
HPLC-FLD-Based Method for the Detection of Sulfonamides in Organic Fertilizers Collected from Poland
(MDPI, 2022)
Antibacterial substances such as sulfonamides are widely used in veterinary medicine to treat many bacterial diseases. After their administration to animals, up to 90% of the initial dose of the antibiotic is excreted in ...
Animal botulism in Poland – laboratory and epidemiological investigations
(National Veterinary Research Institute in Pulawy, 2022)
The aim of the study was to present cases of botulism in animals found in Poland in 2019–2021. The
analytical laboratory diagnosis and difficulties that occurred in the interpretation of the results are described. Material ...
Enterococci—Involvement in Pathogenesis and Therapeutic Potential in Cancer Treatment: A Mini-Review
(2022)
Enterococcus spp. are Gram-positive, heterogeneous lactic acid bacteria inhabiting various
environments. Several species of Enterococci are considered to be able to stimulate the immune
system and play an important role ...
Simultaneous determination of pyrrolizidine and tropane alkaloids in honey by liquid chromatography–mass spectrometry
(National Veterinary Research Institute in Pulawy; Poland, 2022)
Introduction: Pyrrolizidine alkaloids (PAs) and tropane alkaloids (TAs) are natural contaminants of honey and respectively hepatoxic and neurotoxic compounds. Because honey is a popular constituent of the human diet, it ...
Probiotic Potential of Clostridium spp.—Advantages and Doubts
(MDPI, 2022)
Clostridium spp. is a large genus of obligate anaerobes and is an extremely heterogeneous
group of bacteria that can be classified into 19 clusters. Genetic analyses based on the next-
generation sequencing of 16S rRNA ...
Molecular diversity of BoNT-producing clostridia—a still-emerging and challenging problem
(MDPI, 2023)
The diversity of BoNT-producing Clostridia is still a worrying problem for specialistswho explore the evolutionary and taxonomic diversity of C. botulinum. It is also a problem for epidemiologists and laboratory staff ...
Clostridium perfringens - opportunistic foodborne pathogen, its diversity and epidemiological significance
(2023)
The C. perfringens species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and ...
Insect Meals and Insect Antimicrobial Peptides as an Alternative for Antibiotics and Growth Promoters in Livestock Production
(MDPI, 2023)
The extensive use of antibiotics in animal production has led to the development of antibiotic-resistant microorganisms and the search for alternative antimicrobial agents in animal production. One such compound may be ...
Development, in-house validation and application of a method using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) for the quantification of 12 ergot alkaloids in compound feeds
(National Veterinary Research Institute in Pulawy; Poland, 2023)
Introduction: Ergot alkaloids (EAs) are toxic substances naturally produced by Claviceps fungi. These fungi infest a widerange of cereals and grasses. When domestic animals are exposed to EAs through contaminated feeds, ...