Przeglądaj według autora "Grenda, Anna"

Wyświetlanie pozycji 1-12 z 12

    • Animal botulism in Poland – laboratory and epidemiological investigations 

      Grenda, Tomasz; Goldsztejn, Magdalena; Kwiatek, Krzysztof; Kozak, Beata; Grenda, Anna (National Veterinary Research Institute in Pulawy, 2022)
      The aim of the study was to present cases of botulism in animals found in Poland in 2019–2021. The analytical laboratory diagnosis and difficulties that occurred in the interpretation of the results are described. Material ...

    • Attempting to identify bacterial allies in immunotherapy of NSCLC patients 

      Grenda, Anna; Iwan, Ewelina; Krawczyk, Paweł; Frąk, Małgorzata; Chmielewska, Izabela; Bomba, Arkadiusz; Giza, Aleksandra; Rolska-Kopińska, Anna; Szczyrek, Michał; Kieszko, Robert; Kucharczyk, Tomasz; Jarosz, Bożena; Wasyl, Dariusz; Milanowski, Janusz (MDPI, 2022)
      Introduction: Factors other than PD-L1 (Programmed Death Ligand 1) are being sought as predictors for cancer immuno- or chemoimmunotherapy in ongoing studies and long-term ob- servations. Despite high PD-L1 expression ...

    • Botulinum toxin in cancer therapy-current perspectives and limitations 

      Grenda, Tomasz; Grenda, Anna; Krawczyk, Paweł; Kwiatek, Krzysztof (2021)
      Different serotypes of botulinum toxins (BoNTs) act upon different types of SNARE proteins. This property is used in aesthetic medicine to treat certain eye disorders such as crossed eyes (strabismus) and uncontrolled ...

    • Clostridium perfringens - opportunistic foodborne pathogen, its diversity and epidemiological significance 

      Grenda, Tomasz; Jarosz, Aleksandra; Sapała, Magdalena; Grenda, Anna; Patyra, Ewelina; Kwiatek, Krzysztof (2023)
      The C. perfringens species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and ...

    • Enterococci—Involvement in Pathogenesis and Therapeutic Potential in Cancer Treatment: A Mini-Review 

      Grenda, Anna; Grenda, Tomasz; Domaradzki, Piotr; Kwiatek, Krzysztof (2022)
      Enterococcus spp. are Gram-positive, heterogeneous lactic acid bacteria inhabiting various environments. Several species of Enterococci are considered to be able to stimulate the immune system and play an important role ...

    • Gut microbial predictors of firstline immunotherapy efficacy in advanced NSCLC patients 

      Grenda, Anna; Iwan, Ewelina; Kuźnar-Kamińska, Barbara; Bomba, Arkadiusz; Bielińska, Katarzyna; Krawczyk, Paweł; Chmielewska, Izabela; Frąk, Małgorzata; Szczyrek, Michał; Rolska-Kopińska, Anna; Jankowski, Tomasz; Kieszko, Robert; Milanowski, Janusz (Nature, 2025)
      The composition of the gut microbiome of patients with advanced non-small cell lung cancer is currently considered a factor influencing the effectiveness of treatment with immune checkpoint inhibitors. We aimed to evaluate ...

    • Gut resistome of NSCLC patients treated with immunotherapy 

      Iwan, Ewelina; Grenda, Anna; Bomba, Arkadiusz; Bielińska, Katarzyna; Wasyl, Dariusz; Kieszko, Robert; Rolska-Kopińska, Anna; Chmielewska, Izabela; Krawczyk, Paweł; Rybczyńska-Tkaczyk, Kamila; Olejnik, Małgorzata; Milanowski, Janusz (Frontiers, 2024)
      Background: The newest method of treatment for patients with NSCLC (non-small cell lung cancer) is immunotherapy directed at the immune checkpoints PD-1 (Programmed Cell Death 1) and PD-L1 (Programmed Cell Death Ligand 1). ...

    • Molecular diversity of BoNT-producing clostridia—a still-emerging and challenging problem 

      Grenda, Tomasz; Jarosz, Aleksandra; Sapała, Magdalena; Stasiak, Karol; Grenda, Anna; Domaradzki, Piotr; Kwiatek, Krzysztof (MDPI, 2023)
      The diversity of BoNT-producing Clostridia is still a worrying problem for specialistswho explore the evolutionary and taxonomic diversity of C. botulinum. It is also a problem for epidemiologists and laboratory staff ...

    • Opportunistic Features of Non-Clostridium botulinum Strains Containing bont Gene Cluster 

      Grenda, Tomasz; Grenda, Anna; Jakubczyk, Anna; Rybczyńska-Tkaczyk, Kamila (MDPI, 2024)
      The cluster of genes determining the production of botulinum toxins is an attribute of not only the Clostridium botulinum species. This cluster is also found in other members of the Clostridium genus, such as C. baratii, ...

    • Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer 

      Grenda, Anna; Iwan, Ewelina; Chmielewska, Izabela; Krawczyk, Paweł; Giza, Aleksandra; Bomba, Arkadiusz; Frąk, Małgorzata; Rolska, Anna; Szczyrek, Michał; Kieszko, Robert; Kucharczyk, Tomasz; Jarosz, Bożena; Wasyl, Dariusz; Milanowski, Janusz (Springer Open Journal, 2022)
      The significance of Akkermansia bacteria presence in gut micobiome, mainly Akkermansia mucinifila, is currently being investigated in the context of supporting therapy and marker for response to immunotherapy in cancer ...

    • Probiotic Potential of Clostridium spp.—Advantages and Doubts 

      Grenda, Tomasz; Grenda, Anna; Domaradzki, Piotr; Krawczyk, Paweł; Kwiatek, Krzysztof (MDPI, 2022)
      Clostridium spp. is a large genus of obligate anaerobes and is an extremely heterogeneous group of bacteria that can be classified into 19 clusters. Genetic analyses based on the next- generation sequencing of 16S rRNA ...

    • The usefulness of botulinum toxin injections in oncology – clinical and laboratory perspectives 

      Grenda, Tomasz; Makuch, Aleksandra; Grenda, Anna; Domaradzki, Piotr (Elsevier, 2024)
      The use of botulinum toxins in various oncological conditions brings long-term results in the treatment of chronic pain without burdening internal organs, as is the case with the use of opioids. Numerous reports indicate ...