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Genomic evolution of antimicrobial resistance in Escherichia coli

Leekitcharoenphon, Pimlapas; Hans Kristofer Johansson, Markus; Munk, Patrick; Malorny, Burkhard; Skarżyńska, Magdalena; Wadepohl, Katharina; Moyano, Gabriel; Hesp, Ayla; T. Veldman, Kees; Bossers, Alex; EFFORT Consortium; Zając, Magdalena; Wasyl, Dariusz (2021)

The emergence of antimicrobial resistance (AMR) is one of the biggest health threats globally. In addition, the use of antimicrobial drugs in humans and livestock is considered an important driver of antimicrobial resistance. ...

Risk Factors for Antimicrobial Resistance in Turkey Farms: A Cross-Sectional Study in Three European Countries

Horie, Mayu; Yang, Dongsheng; Joosten, Philip; Munk, Patrick; Wadepohl, Katharina; Chauvin, Claire; Moyano, Gabriel; Skarżyńska, Magdalena; Dewulf, Jeroen; Aarestrup, Frank M.; Blaha, Thomas; Sanders, Pascal; Gonzalez-Zorn, Bruno; Wasyl, Dariusz; Wagenaar, Jaap; Heederik, Dick; Mevius, Dik; Schmitt, Heike; Smit, Lidwien; Van Gompel, Liese (2021)

Food-producing animals are an important reservoir and potential source of transmission ofantimicrobial resistance (AMR) to humans. However, research on AMR in turkey farms is limited.This study aimed to identify risk factors ...

Determinants for antimicrobial resistance genes in farm dust on 333 poultry and pig farms in nine European countries

Luiken, Roosmarijn; Heederik, Dick JJ.; Scherpenisse, Peter; Gompel Van, Liese; Heijnsbergen van, Eri; Greve, Gerdit; Jongerius-Gortemaker, Betty; Tersteeg-Zijderveld, Monique; Fischer, Jennie; Juraschek, Katharina; Skarżyńska, Magdalena; Zając, Magdalena; Wasyl, Dariusz; Wagenar, Jaap; Smit, Lidwien; Wouters, Inge; Mevius, Dik; Schmitt, Heike (Elsevier, 2022)

Livestock feces with antimicrobial resistant bacteria reaches the farm floor, manure pit, farm land and wider environment by run off and aerosolization. Little research has been done on the role of dust in the spread of ...

Risk factors for the abundance of antimicrobial resistance genes aph(3′)-III, erm(B), sul2 and tet(W) in pig and broiler faeces in nine European countries

Yang, Dongsheng; Heederik, Dick J. J.; Mevius, Dik J.; Scherpenisse, Peter; Luiken, Roosmarijn E. C.; Van Gompel, Liese; Skarżyńska, Magdalena; Wadepohl, Katharina; Chauvin, Claire; Heijnsbergen van, Eri; Wouters, Inge M.; Greve, Gerdit D.; Jongerius-Gortemaker, Betty G. M.; Tersteeg-Zijderveld, Monique; Zając, Magdalena; Wasyl, Dariusz; Juraschek, Katharina; Fischer, Jennie; Wagenaar, Jaap A.; Smit, Lidwien A. M.; Schmitt, Heike; on behalf of the EFFORT consortium (2021)

Objectives: The occurrence and zoonotic potential of antimicrobial resistance (AMR) in pigs and broilers has been studied intensively in past decades. Here, we describe AMR levels of European pig and broiler farms and ...

Mixed Infection of Mycobacterium szulgai, M. lentiflavum, and Gram-Negative Bacteria as a Cause of Death in a Brown Caiman Caiman crocodylus: A Case Report

Maluta, Aleksandra; Zając, Magdalena; Krajewska-Wędzina, Monika; Wasyl, Dariusz; Heckers, Kim; Didkowska, Anna; Anusz, Krzysztof (MDPI, 2022)

This paper describes a fatal case of nontuberculosis mycobacteriosis in a four-year-old brown caiman kept in captivity. Although the clinical signs were asymptomatic, severe gross lesions were observed, namely necrotic ...

Multicentre evaluation of a selective isolation protocol for detection of mcr ‐positive E. coli and Salmonella spp. in food‐producing animals and meat

Perrin-Guyomard, Agnes; Granier, Sophie A.; Slettemeas, Jannice Schau; Anjum, Muna; Randall, Luke; AbuOun, Manal; Natalie, Pauly; Irrgang, Alexandra; Hammerl, Jens Andre; Kjeldgaard, Jette Sejer; Hammerum, Anette; Franco, Alessia; Skarżyńska, Magdalena; Kamińska, Ewelina; Wasyl, Dariusz; Dierikx, Cindy; Borjesson, Stefan; Geurts, Yvon; Haenni, Marisa; Veldman, Kees (2022)

This study was conducted to evaluate the performance of a screening protocol to detect and isolate mcr-positive Escherichia coli and Salmonella spp. from animal caecal content and meat samples. We used a multicentre ...

Antimicrobial resistance genes aph(3′)-III, erm(B), sul2 and tet(W) abundance in animal faeces, meat, production environments and human faeces in Europe

Yang, Dongsheng; Heederik, Dick J. J.; Scherpenisse, Peter; Van Gompel, Liese; Luiken, Roosmarijn E. C.; Wadepohl, Katharina; Skarżyńska, Magdalena; Van Heijnsbergen, Eri; Wouters, Inge M.; Greve, Gerdit D.; Jongerius-Gortemaker, Betty G. M.; Tersteeg-Zijderveld, Monique; Portengen, Lützen; Juraschek, Katharina; Fischer, Jennie; Zając, Magdalena; Wasyl, Dariusz (OXFORD Academic, 2022)

Real-time quantitative PCR (qPCR) is an affordable method to quantify antimicrobial resistance gene (ARG) targets, allowing comparisons of ARG abundance along animal production chains. Objectives We present a comparison ...

Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer

Grenda, Anna; Iwan, Ewelina; Chmielewska, Izabela; Krawczyk, Paweł; Giza, Aleksandra; Bomba, Arkadiusz; Frąk, Małgorzata; Rolska, Anna; Szczyrek, Michał; Kieszko, Robert; Kucharczyk, Tomasz; Jarosz, Bożena; Wasyl, Dariusz; Milanowski, Janusz (Springer Open Journal, 2022)

The significance of Akkermansia bacteria presence in gut micobiome, mainly Akkermansia mucinifila, is currently being investigated in the context of supporting therapy and marker for response to immunotherapy in cancer ...

Draft genome sequences data of four Salmonella enterica subsp. enterica serovar Dublin archival strains originating from animals in Poland, 1956 – 1957

Skóra, Milena; Kwit, Renata; Zając, Magdalena; Pietruk, Marta; Skarżyńska, Magdalena; Skrzypiec, Ewelina; Katarzyna, Tłuścik; Lalak, Anna; Wasyl, Dariusz (Elsevier BV, 2022)

Salmonella enterica subsp. enterica serovar Dublin (S. Dublin) is a zoonotic pathogen causing infections in animals, especially in cattle. In this study, we report draft genome sequences of four S. Dublin isolated between ...

Attempting to identify bacterial allies in immunotherapy of NSCLC patients

Grenda, Anna; Iwan, Ewelina; Krawczyk, Paweł; Frąk, Małgorzata; Chmielewska, Izabela; Bomba, Arkadiusz; Giza, Aleksandra; Rolska-Kopińska, Anna; Szczyrek, Michał; Kieszko, Robert; Kucharczyk, Tomasz; Jarosz, Bożena; Wasyl, Dariusz; Milanowski, Janusz (MDPI, 2022)

Introduction: Factors other than PD-L1 (Programmed Death Ligand 1) are being sought as predictors for cancer immuno- or chemoimmunotherapy in ongoing studies and long-term ob- servations. Despite high PD-L1 expression ...