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The Role of Bcl-2 and Beclin-1 Complex in “Switching” between Apoptosis and Autophagy in Human Glioma Cells upon LY294002 and Sorafenib Treatment

Zająć, Adrian; Maciejczyk, Aleksandra; Sumorek-Wiadro, Joanna; Filipek, Karol; Deryło, Kamil; Langner, Ewa; Pawelec, Jarosław; Wasiak, Magdalena; Ścibiorski, Mateusz; Rzeski, Wojciech; Tchórzewski, Marek; Reichert, Michał; Joanna Jakubowicz-Gil, Joanna (mdpi, 2023)

Background: Gliomas are the most malignant tumors of the central nervous system. One of the factors in their high drug resistance is avoiding programmed death (PCD) induction. This is related to the overexpression of ...