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Pathogens

dc.contributor.authorDudek, Katarzyna
dc.contributor.authorSevimli, Umit
dc.contributor.authorMigliore, Sergio
dc.contributor.authorJafarizadeh, Amirreza
dc.contributor.authorLoria, Guido R.
dc.contributor.authorNicholas, Robin A.J.
dc.date.accessioned2022-01-13T10:48:06Z
dc.date.available2022-01-13T10:48:06Z
dc.date.issued2022
dc.identifierhttps://dspace.piwet.pulawy.pl/xmlui/handle/123456789/167
dc.identifier.issn2076-0817
dc.identifier.urihttps://www.mdpi.com/2076-0817/11/1/75/htm
dc.description.abstractMycoplasmas cause some of the most economically important diseases of sheep and goats, including diseases listed by the World Organisation for Animal Health (OIE) such as contagious caprine pleuropneumonia (CCPP) and contagious agalactia (CA). Other important mycoplasma diseases include chronic respiratory and arthritic syndrome (CRAS) and atypical pneumonia, both present on all continents where small ruminants are farmed. Unfortunately, owing to a lack of investment, most commercial vaccines for these diseases are of poor quality, being mostly composed of killed bacteriocins of dubious or unknown efficacy. Several Mediterranean laboratories produce autogenous vaccines, but these can only be used on farms where outbreaks have been officially declared, and consequently have limited impact on disease nationally. Effective live vaccines are available, but their use is often restricted because of safety concerns. With the necessary safeguards in place, we argue for their greater use. This review examines reported vaccines for mycoplasma diseases of small ruminants and attempts to identify new candidate antigens that may enable the development of improved products. Vaccines for CCPP are covered elsewhere.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectsmall ruminantsen_US
dc.subjectmycoplasmaen_US
dc.subjectvaccinesen_US
dc.titleVaccines for Mycoplasma Diseases of Small Ruminants: A Neglected Area of Researchen_US
dc.typeArticleen_US
dcterms.bibliographicCitation2022 vol. 11 nr 1 s. 75
dcterms.titlePathogens
dc.identifier.doihttps://doi.org/10.3390/pathogens11010075


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